BDBM50185983 3,9-dibenzyl-1,7-dihydroxymethyl-6,12-diphenyl-3,9-diazahexacyclo[6.4.0.0(2.7)0(4.11)0(5.10)]dodecane::CHEMBL379683

SMILES OC[C@@]12C3C4C1N(Cc1ccccc1)C1C(C(N3Cc3ccccc3)[C@@]1(CO)[C@H]4c1ccccc1)[C@H]2c1ccccc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185983   

TargetATP-dependent translocase ABCB1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50185983(3,9-dibenzyl-1,7-dihydroxymethyl-6,12-diphenyl-3,9...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of P-glycoproteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50185983(3,9-dibenzyl-1,7-dihydroxymethyl-6,12-diphenyl-3,9...)
Affinity DataIC50: 1.33E+4nMAssay Description:Cytotoxicity against mouse MDR1 transfected L5178YvMDR cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed