BDBM50185982 1,7-dihydroxymethyl-3,9-dimethyl-6,12-diphenyl-3,9-diazahexacyclo[6.4.0.0 2.7.0 4.11.0. 5.10]dodecane::CHEMBL427029

SMILES CN1C2C3C4N(C)C5C(C1[C@@]5(CO)[C@H]3c1ccccc1)[C@@H](c1ccccc1)[C@]24CO

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185982   

TargetATP-dependent translocase ABCB1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50185982(1,7-dihydroxymethyl-3,9-dimethyl-6,12-diphenyl-3,9...)
Affinity DataIC50: 7.50E+3nMAssay Description:Cytotoxicity against mouse MDR1 transfected L5178YvMDR cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50185982(1,7-dihydroxymethyl-3,9-dimethyl-6,12-diphenyl-3,9...)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of P-glycoproteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed