BDBM50185780 (4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluorophenyl)methanone::CHEMBL210230

SMILES Fc1ccc(CCC2CCN(CC2)C(=O)c2ccccc2F)c(F)c1

InChI Key InChIKey=MYAIOSJLOIUJFU-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50185780   

Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185780((4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluoro...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185780((4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluoro...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185780((4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluoro...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185780((4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluoro...)
Affinity DataKi:  110nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185780((4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluoro...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185780((4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluoro...)
Affinity DataKi: >9.00E+3nMAssay Description:Binding affinity to human IKrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185780((4-(2,4-difluorophenethyl)piperidin-1-yl)(2-fluoro...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed