BDBM50185750 CHEMBL3824229

SMILES Cc1nc(Nc2nc(=O)cc(CSc3nnnn3-c3ccccc3)[nH]2)nc2ccccc12

InChI Key InChIKey=BPNPOVCTXJWVNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185750   

TargetHistone-lysine N-methyltransferase EZH2(Human)
College of Chemical and Environmental Engineering

Curated by ChEMBL
LigandPNGBDBM50185750(CHEMBL3824229)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of PRC2 EZH2 sub unit (unknown origin) assessed as inhibition of SAM-mediated methyl transfer process preincubated for 15 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2017
Entry Details Article
PubMed