BDBM50185463 3-(benzo[d][1,3]dioxol-5-yl)-4-(1-phenyl-5-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy)-1H-pyrazol-3-yl)butanoic acid::CHEMBL438080

SMILES OC(=O)CC(Cc1cc(OCCc2ccc3CCCNc3n2)n(n1)-c1ccccc1)c1ccc2OCOc2c1

InChI Key InChIKey=XHPZRPHYLGZLTO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50185463   

TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185463(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-phenyl-5-(2-(5,6...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of alpha-v-beta-3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185463(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-phenyl-5-(2-(5,6...)
Affinity DataIC50: 1.18nMAssay Description:Inhibition of alpha-v-beta-3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185463(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-phenyl-5-(2-(5,6...)
Affinity DataIC50: 3.27nMAssay Description:Inhibition of alpha-v-beta-5 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185463(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-phenyl-5-(2-(5,6...)
Affinity DataIC50: 352nMAssay Description:Inhibition of alphavbeta6 integrin in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185463(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-phenyl-5-(2-(5,6...)
Affinity DataIC50: 24.4nMAssay Description:Inhibition of alpha-2b-beta-3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed