BDBM50185457 3-(benzo[d][1,3]dioxol-5-yl)-4-(1-benzyl-5-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy)-1H-pyrazol-3-yl)butanoic acid::CHEMBL207289

SMILES OC(=O)CC(Cc1cc(OCCc2ccc3CCCNc3n2)n(Cc2ccccc2)n1)c1ccc2OCOc2c1

InChI Key InChIKey=KRAZOLZZRSRPAE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50185457   

TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185457(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-benzyl-5-(2-(5,6...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of alpha-v-beta-3 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185457(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-benzyl-5-(2-(5,6...)
Affinity DataIC50: 1.84nMAssay Description:Inhibition of alpha-v-beta-5 integrin in 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185457(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-benzyl-5-(2-(5,6...)
Affinity DataIC50: 13.5nMAssay Description:Inhibition of alpha-2b-beta-3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185457(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-benzyl-5-(2-(5,6...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of alpha-v-beta-3 integrin by SPRAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50185457(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-benzyl-5-(2-(5,6...)
Affinity DataIC50: 2.11E+3nMAssay Description:Inhibition of alphavbeta6 integrin in HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed