BDBM50185314 CHEMBL3822963

SMILES COCC(=O)N1CC[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)c2cc(Cc3ccccc3)ccc12

InChI Key InChIKey=HPMVNXXVOVDOMU-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50185314   

TargetMu-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50185314(CHEMBL3822963)
Affinity DataEC50:  3nMAssay Description:Agonist activity at rat MOR transfected in rat C6 cell membranes after 1 hr by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50185314(CHEMBL3822963)
Affinity DataEC50:  67nMAssay Description:Agonist activity at rat DOR transfected in rat C6 cell membranes after 1 hr by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50185314(CHEMBL3822963)
Affinity DataEC50: >1.70E+3nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50185314(CHEMBL3822963)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]diprenorphine from rat MOR transfected in rat C6 cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50185314(CHEMBL3822963)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]diprenorphine from rat DOR transfected in rat C6 cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50185314(CHEMBL3822963)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]diprenorphine from human KOR expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2017
Entry Details Article
PubMed