BDBM50185003 CHEMBL3824264::US10351548, Compound JJ31

SMILES Fc1ccc(Cn2cccc(C(=O)Nc3ccc4NC(=O)\C(=C/c5cnc[nH]5)c4c3)c2=O)cc1F

InChI Key InChIKey=DJFVVRAJTMRMJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185003   

Target3-phosphoinositide-dependent protein kinase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50185003(CHEMBL3824264 | US10351548, Compound JJ31)
Affinity DataIC50: 512nMAssay Description:Inhibition of PDK1 (unknown origin) by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50185003(CHEMBL3824264 | US10351548, Compound JJ31)
Affinity DataIC50: 512nMAssay Description:Factor IX is a key component of the plasma system that forms a fibrin clot at a site of vascular injury. The activity of Factor IXa is measured by mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details
Go to US Patent