BDBM50184883 2-(2-fluorophenyl)-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridine::2-[2-fluorophenyl]-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine::CHEMBL205427

SMILES Fc1ccccc1-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1

InChI Key InChIKey=OWHLMAYULDWFQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184883   

TargetTGF-beta receptor type-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50184883(2-(2-fluorophenyl)-4-(3-(pyridin-2-yl)-1H-pyrazol-...)
Affinity DataIC50: 59nMAssay Description:Inhibition of TGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50184883(2-(2-fluorophenyl)-4-(3-(pyridin-2-yl)-1H-pyrazol-...)
Affinity DataIC50: 59nMAssay Description:Displacement of rhodamine green fluorescently labeled ATP from recombinant GST-ALK5 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed