BDBM50184787 CHEMBL3823308

SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(C)c1Cl)-c1ccncc1

InChI Key InChIKey=AICVIWJSFCXEOX-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50184787   

TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50184787(CHEMBL3823308)
Affinity DataKd:  133nMAssay Description:Binding affinity to His-tagged human WDR5 expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50184787(CHEMBL3823308)
Affinity DataIC50: 104nMAssay Description:Inhibition of 10mer-Thr-FAM probe binding to His-tagged human WDR5 expressed in Escherichia coli incubated for 2 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50184787(CHEMBL3823308)
Affinity DataIC50: 104nMAssay Description:Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2018
Entry Details Article
PubMed