BDBM50184430 1-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine::CHEMBL203689

SMILES CN1CCc2ccccc2Cc2c(O)cccc2CC1

InChI Key InChIKey=YAOWMUKUYWGVDH-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50184430   

TargetD(2) dopamine receptor(Human)
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184430(1-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d...)
Affinity DataKi:  7.90nMAssay Description:Inhibition of D2L dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184430(1-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]SCH 23390 from D1 dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184430(1-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d...)
Affinity DataKi:  10.4nMAssay Description:Inhibition of D5 dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184430(1-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d...)
Affinity DataKi:  64.1nMAssay Description:Inhibition of D1 dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184430(1-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d...)
Affinity DataKi:  84nMAssay Description:Displacement of [3H]spiperone from D2L dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184430(1-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d...)
Affinity DataKi:  215nMAssay Description:Binding affinity to D3 dopamine receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed