BDBM50183971 6-chloro-4-(1-(naphthalen-2-ylmethyl)piperidin-4-ylamino)-1-(2,2,2-trifluoroethyl)quinazolin-2(1H)-one::CHEMBL204508

SMILES FC(F)(F)Cn1c2ccc(Cl)cc2c(NC2CCN(Cc3ccc4ccccc4c3)CC2)nc1=O

InChI Key InChIKey=PHCHRPWAMGPRTQ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50183971   

TargetMelanin-concentrating hormone receptor 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183971(6-chloro-4-(1-(naphthalen-2-ylmethyl)piperidin-4-y...)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183971(6-chloro-4-(1-(naphthalen-2-ylmethyl)piperidin-4-y...)
Affinity DataIC50: 62nMAssay Description:Inhibition of MCH-mediated calcium release in whole IMR32 cells by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183971(6-chloro-4-(1-(naphthalen-2-ylmethyl)piperidin-4-y...)
Affinity DataKi:  150nMAssay Description:Binding affinity to hERG stably transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed