BDBM50183739 CHEMBL208051::N-hydroxy-4-((4-((2-methylquinolin-4-yl)methoxy)benzamido)methyl)-1-(methylsulfonyl)piperidine-4-carboxamide

SMILES Cc1cc(COc2ccc(cc2)C(=O)NCC2(CCN(CC2)S(C)(=O)=O)C(=O)NO)c2ccccc2n1

InChI Key InChIKey=WIFSQEZIILGJQU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50183739   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50183739(N-hydroxy-4-((4-((2-methylquinolin-4-yl)methoxy)be...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50183739(N-hydroxy-4-((4-((2-methylquinolin-4-yl)methoxy)be...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of LPS-stimulated TNFalpha production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50183739(N-hydroxy-4-((4-((2-methylquinolin-4-yl)methoxy)be...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed