BDBM50182125 CHEMBL204687::bis(2-nitro-4-(trifluoromethyl)phenyl)sulfane

SMILES [O-][N+](=O)c1cc(ccc1Sc1ccc(cc1[N+]([O-])=O)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=JZOKZEROYRPYIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182125   

TargetThioredoxin reductase 1, cytoplasmic/2, mitochondrial/3(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50182125(bis(2-nitro-4-(trifluoromethyl)phenyl)sulfane | CH...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human TrxRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThioredoxin reductase(Plasmodium falciparum (isolate 3D7))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50182125(bis(2-nitro-4-(trifluoromethyl)phenyl)sulfane | CH...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Plasmodium falciparum TrxRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed