BDBM50182106 4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-1-yl)propyl)piperidin-4-yl)-5-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL380361

SMILES Cc1cccc2OCC(=O)N(C3CCN(CCCn4nc(c5CN(CCc45)S(C)(=O)=O)-c4ccc(Br)cc4)CC3)c12

InChI Key InChIKey=QQNJSLZFYGMUKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182106   

TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182106(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182106(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 170nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed