BDBM50182095 1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-1-yl)-2-hydroxypropyl)piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-one::CHEMBL205748

SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)NCc2ccccc12)-c1ccc(Br)cc1

InChI Key InChIKey=AFUFPTUEAKAICH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182095   

TargetHLA class II histocompatibility antigen gamma chain(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182095(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MHC2 invariant chainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182095(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Affinity DataIC50: 65nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed