BDBM50181311 4-Amino-3-(6-morpholin-4-ylbenzimidazol-2-yl)hydroquinolin-2-one::4-amino-3-(6-morpholino-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one::CHEMBL204426

SMILES Nc1c(-c2nc3ccc(cc3[nH]2)N2CCOCC2)c(=O)[nH]c2ccccc12

InChI Key InChIKey=JZGWDENJLOXKLZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50181311   

LigandPNGBDBM50181311(4-amino-3-(6-morpholino-1H-benzo[d]imidazol-2-yl)q...)
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50181311(4-amino-3-(6-morpholino-1H-benzo[d]imidazol-2-yl)q...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chiron

Curated by ChEMBL
LigandPNGBDBM50181311(4-amino-3-(6-morpholino-1H-benzo[d]imidazol-2-yl)q...)
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against FGFR1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50181311(4-amino-3-(6-morpholino-1H-benzo[d]imidazol-2-yl)q...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against VEGFR1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50181311(4-amino-3-(6-morpholino-1H-benzo[d]imidazol-2-yl)q...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50181311(4-amino-3-(6-morpholino-1H-benzo[d]imidazol-2-yl)q...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chiron

Curated by ChEMBL
LigandPNGBDBM50181311(4-amino-3-(6-morpholino-1H-benzo[d]imidazol-2-yl)q...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed