BDBM50181065 2-chloro-6-((2-chloropyridin-4-yl)methoxy)isonicotinonitrile::CHEMBL206296

SMILES Clc1cc(COc2cc(cc(Cl)n2)C#N)ccn1

InChI Key InChIKey=MNMWRNWFNYWLKI-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50181065   

TargetMetabotropic glutamate receptor 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50181065(2-chloro-6-((2-chloropyridin-4-yl)methoxy)isonicot...)
Affinity DataIC50: 72nMAssay Description:Inhibition of mGlu5 receptor by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50181065(2-chloro-6-((2-chloropyridin-4-yl)methoxy)isonicot...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]MPEP from recombinant human mGlu5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed