BDBM50180998 (3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-6-(2-hydroxyethyl)-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL381554

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@H](CCO)SC(C)(C)[C@@H]1C(=O)NO

InChI Key InChIKey=MGQZHWBYKGXMDX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50180998   

TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50180998((3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydr...)
Affinity DataIC50: 21nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50180998((3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydr...)
Affinity DataIC50: 23nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50180998((3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydr...)
Affinity DataIC50: 15nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed