BDBM50180609 3-[4-(4-Chlorophenylethynyl)benzoyl]nonanoic acid 1j::CHEMBL199666

SMILES CCCCCCC(CC(O)=O)C(=O)c1ccc(cc1)C#Cc1ccc(Cl)cc1

InChI Key InChIKey=UOBFNJXLVSPHNN-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50180609   

TargetMatrix metalloproteinase-9(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50180609(3-[4-(4-Chlorophenylethynyl)benzoyl]nonanoic acid ...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibitory activity against MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50180609(3-[4-(4-Chlorophenylethynyl)benzoyl]nonanoic acid ...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target72 kDa type IV collagenase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50180609(3-[4-(4-Chlorophenylethynyl)benzoyl]nonanoic acid ...)
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50180609(3-[4-(4-Chlorophenylethynyl)benzoyl]nonanoic acid ...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)