BDBM50180512 1-methyl-5-vinyl-9,10-dihydrophenanthrene-2,7-diol::CHEMBL205119

SMILES Cc1c(O)ccc-2c1CCc1cc(O)cc(C=C)c-21

InChI Key InChIKey=GEXAPRXWKRZPCK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50180512   

TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180512(1-methyl-5-vinyl-9,10-dihydrophenanthrene-2,7-diol...)
Affinity DataIC50: 12nMAssay Description:Binding affinity to ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180512(1-methyl-5-vinyl-9,10-dihydrophenanthrene-2,7-diol...)
Affinity DataIC50: 240nMAssay Description:Binding affinity to ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetdTDP-4-dehydrorhamnose reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of California

Curated by ChEMBL
LigandPNGBDBM50180512(1-methyl-5-vinyl-9,10-dihydrophenanthrene-2,7-diol...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis RmlD assessed as inhibition of dTDP-beta-6-deoxy-L-lyxo-4-hexulose to dTDP-beta-L-rhamnose conversionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Human)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50180512(1-methyl-5-vinyl-9,10-dihydrophenanthrene-2,7-diol...)
Affinity DataIC50: 2.33E+4nMAssay Description:Inhibition of OAT1 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 8(Human)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50180512(1-methyl-5-vinyl-9,10-dihydrophenanthrene-2,7-diol...)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of OAT3 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed