BDBM50179930 2'-Fluoro-5'-[7-(1-hydroxy-1-methyl-ethyl)-imidazo[1,2-a]pyridin-3-yl]-biphenyl-2-carbonitrile::CHEMBL206196

SMILES CC(C)(O)c1ccn2c(cnc2c1)-c1ccc(F)c(c1)-c1ccccc1C#N

InChI Key InChIKey=SOLFHEZOCDBPSQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179930   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179930(2'-Fluoro-5'-[7-(1-hydroxy-1-methyl-ethyl)-imidazo...)
Affinity DataKi:  4.35nMAssay Description:Displacement of [3H]Ro 15-1788 from human GABA-Aalpha1 receptor plus beta-3-gamma-2 expressed in mouse L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179930(2'-Fluoro-5'-[7-(1-hydroxy-1-methyl-ethyl)-imidazo...)
Affinity DataKi:  5.16nMAssay Description:Displacement of [3H]Ro 15-1788 from human GABA-Aalpha3 receptor plus beta-3-gamma-2 expressed in mouse L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed