BDBM50179646 1-(1-butyl-4-oxoimidazolidin-2-ylidene)-3-(3-chlorophenyl)urea::CHEMBL203720

SMILES CCCCn1cc(O)nc1NC(=O)Nc1cccc(Cl)c1

InChI Key InChIKey=RJXINBOETHQHOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179646   

TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50179646(1-(1-butyl-4-oxoimidazolidin-2-ylidene)-3-(3-chlor...)
Affinity DataIC50: 680nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50179646(1-(1-butyl-4-oxoimidazolidin-2-ylidene)-3-(3-chlor...)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]MPEP from mGluR5d in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed