BDBM50179640 1-(3-chlorophenyl)-3-(1-oxo-hexahydropyrrolo[1,2-e]imidazol-3-ylidene)urea::CHEMBL201827

SMILES Oc1nc(NC(=O)Nc2cccc(Cl)c2)n2CCCc12

InChI Key InChIKey=UMSMTONOMSDWIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179640   

TargetMetabotropic glutamate receptor 5(Rat)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50179640(1-(3-chlorophenyl)-3-(1-oxo-hexahydropyrrolo[1,2-e...)
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of [3H]MPEP from mGluR5d in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50179640(1-(3-chlorophenyl)-3-(1-oxo-hexahydropyrrolo[1,2-e...)
Affinity DataIC50: 800nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed