BDBM50179421 (rac)-2-(6-(3-aminopyrrolidin-1-yl)pyrimidin-4-ylamino)thiazole-5-carbonitrile::CHEMBL381817

SMILES NC1CCN(C1)c1cc(Nc2ncc(s2)C#N)ncn1

InChI Key InChIKey=FHVQNINHKOYUII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179421   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179421((rac)-2-(6-(3-aminopyrrolidin-1-yl)pyrimidin-4-yla...)
Affinity DataIC50: 16nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179421((rac)-2-(6-(3-aminopyrrolidin-1-yl)pyrimidin-4-yla...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human KDR expressed in HEK293 cells by KDR autophosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed