BDBM50179140 (R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-(((S)-4-methyl-2-oxooxazolidin-3-yl)methyl)piperidin-1-yl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL204078

SMILES C[C@H]1COC(=O)N1CC1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCCCC1

InChI Key InChIKey=GUUMVPUVSBGKBI-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50179140   

TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179140((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  400nMAssay Description:Activity against human MC5R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179140((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  8.60nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179140((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  640nMAssay Description:Activity against human MC3R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179140((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 840nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179140((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 2.40E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1BR expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179140((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  2.10E+3nMAssay Description:Activity against human MC1BR by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179140((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 220nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179140((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 4.5nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed