BDBM50178976 5,7-dibromo-6-(4-hydroxy-3-isopropylphenoxy)-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL378593

SMILES CC(C)c1cc(Oc2c(Br)cc3nc(cc(O)c3c2Br)C(O)=O)ccc1O

InChI Key InChIKey=DXDHCVCAJKZAHT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50178976   

TargetThyroid hormone receptor beta(Human)
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50178976(5,7-dibromo-6-(4-hydroxy-3-isopropylphenoxy)-4-oxo...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human TR-beta-1 by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50178976(5,7-dibromo-6-(4-hydroxy-3-isopropylphenoxy)-4-oxo...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human TR-alpha-1 by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50178976(5,7-dibromo-6-(4-hydroxy-3-isopropylphenoxy)-4-oxo...)
Affinity DataIC50: 251nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50178976(5,7-dibromo-6-(4-hydroxy-3-isopropylphenoxy)-4-oxo...)
Affinity DataIC50: 51.3nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed