BDBM50178699 CHEMBL3813836

SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NC[C@@H](O)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1

InChI Key InChIKey=RZZQOPUUGKMRNW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178699   

TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178699(CHEMBL3813836)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178699(CHEMBL3813836)
Affinity DataIC50: 55nMAssay Description:Inhibition of CETP in human whole plasma assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to LDL/VLDLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178699(CHEMBL3813836)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of recombinant human ERG flux expressed in HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed