BDBM50178587 CHEMBL206644::N-((4-ethyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methyl)-2-(5-fluoro-1H-indol-3-yl)ethanamine

SMILES CCN1CC(CNCCc2c[nH]c3ccc(F)cc23)Oc2ccccc12

InChI Key InChIKey=XKYLLYRSYNHDDE-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178587   

Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178587(N-((4-ethyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-y...)
Affinity DataEC50:  90nMAssay Description:Intrinsic activity assessed by stimulation of [35S]GTP-gamma-S binding in CHO cells expressing 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178587(N-((4-ethyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-y...)
Affinity DataKi:  15.3nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178587(N-((4-ethyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-y...)
Affinity DataKi:  15.3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed