BDBM50178428 (S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-one::2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE::CHEMBL383705

SMILES CC(C)[C@H](N)C(=O)N1CCCC1

InChI Key InChIKey=IHBAVXVTGLANPI-UHFFFAOYSA-N

Data  3 KI  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50178428   

TargetDipeptidyl peptidase 4(Human)
Santhera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataIC50: 1.53E+5nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Santhera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataIC50: 2.23E+5nMAssay Description:In vitro inhibition of porcine Dipeptidylpeptidase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Santhera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition of human Dipeptidylpeptidase IV.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2020
Entry Details Article
PubMed
TargetDipeptidyl peptidase IV(Porphyromonas gingivalis)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of Porphyromonas gingivalis N-terminal His-tagged DPP4 expressed in Escherichia coli using Gly-Pro-p-nitroanilide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2020
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Santhera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2020
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Bovine)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of bovine DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2020
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataIC50: 1.53E+5nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2020
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Santhera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataKi:  470nMAssay Description:In vitro test for inhibitory activity against human dipeptidyl peptidase IV.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDipeptidyl peptidase 4(Human)
Santhera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Santhera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178428(2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE | (...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to DPP-4 (unknown origin) using Gly-Pro-pNA as substrate assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed