BDBM50178421 2-((2-(4-fluoro-1,3-dioxo-2-phenyl-2,3-dihydro-1H-inden-2-yl)ethyl)(methyl)amino)acetic acid::CHEMBL205828

SMILES CN(CCC1(C(=O)c2cccc(F)c2C1=O)c1ccccc1)CC(O)=O

InChI Key InChIKey=FFLRDFJKUULSPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178421   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178421(2-((2-(4-fluoro-1,3-dioxo-2-phenyl-2,3-dihydro-1H-...)
Affinity DataIC50: 85nMAssay Description:Inhibition of uptake of [14C]glycine into human JAR cells expressing human GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed