BDBM50178416 (2S)-1-(2-(4,5-dichloro-6-methoxy-1,3-dioxo-2-phenyl-2,3-dihydro-1H-inden-2-yl)ethyl)pyrrolidine-2-carboxylic acid::CHEMBL380743

SMILES COc1cc2C(=O)C(CCN3CCC[C@H]3C(O)=O)(C(=O)c2c(Cl)c1Cl)c1ccccc1

InChI Key InChIKey=GSEHNHXNKLHNBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178416   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178416((2S)-1-(2-(4,5-dichloro-6-methoxy-1,3-dioxo-2-phen...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of uptake of [14C]glycine into human JAR cells expressing human GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed