BDBM50177561 (R)-N-((R)-3-(4-chlorophenyl)-1-(4-(2-(diethylamino)-1-(2-fluorophenyl)ethyl)piperazin-1-yl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL377961

SMILES CCN(CC)CC(N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)c1ccccc1F

InChI Key InChIKey=PUBNSQFRKLLQSF-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50177561   

TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50177561((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(2-(diethylamin...)
Affinity DataKi:  20nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50177561((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(2-(diethylamin...)
Affinity DataKi:  41nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50177561((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(2-(diethylamin...)
Affinity DataKi:  950nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC5R expressed in HEK293 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50177561((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(2-(diethylamin...)
Affinity DataKi:  5.80E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC1R expressed in HEK293 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50177561((R)-N-((R)-3-(4-chlorophenyl)-1-(4-(2-(diethylamin...)
Affinity DataKi:  7.00E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from cloned human MC3R expressed in HEK293 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed