BDBM50177275 CHEMBL204968::N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methylquinolin-6-yl)-3-(4-(trifluoromethoxy)phenyl)propanamide

SMILES CN(C)CCN(C)c1cc(C)c2cc(NC(=O)CCc3ccc(OC(F)(F)F)cc3)ccc2n1

InChI Key InChIKey=ZRGODGYQZOLGQP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177275   

TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50177275(N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-met...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human MCH1 receptor by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50177275(N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-met...)
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in CHO cell by WC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50177275(N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-met...)
Affinity DataIC50: 724nMAssay Description:Displacement of [3H]myo-inositol from human MCH1 receptor expressed in CHO cell by IP3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed