BDBM50177022 CHEMBL3814424

SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)(F)F)Cc1cccc2ccoc12

InChI Key InChIKey=UMJCCCZKGYJSIX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50177022   

Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50177022(CHEMBL3814424)
Affinity DataIC50: 339nMAssay Description:Inhibition of Staphylococcus aureus Newman 6His-tagged CrtN expressed in Escherichia coli BL21(DE3) using diapophytoene as substrate assessed as pigm...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50177022(CHEMBL3814424)
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by Qpatch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50177022(CHEMBL3814424)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential after 3 mins by QPatch testMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50177022(CHEMBL3814424)
Affinity DataIC50: 300nMAssay Description:Inhibition of Staphylococcus aureus Newman 6His-tagged CrtN expressed in Escherichia coli BL21 (DE3)/pET28a::CrtN assessed as reduction in staphyloxa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50177022(CHEMBL3814424)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of CrtN in methicillin-resistant Staphylococcus aureus LAC USA300 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrop...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50177022(CHEMBL3814424)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of CrtN in methicillin-resistant Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotome...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain MW2))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50177022(CHEMBL3814424)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of CrtN in methicillin-resistant Staphylococcus aureus USA400 MW2 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrop...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed