BDBM50175839 4-((1H-imidazol-4-yl)methyl)-1-(3-phenoxypropyl)piperidine::CHEMBL200267

SMILES C(COc1ccccc1)CN1CCC(Cc2cnc[nH]2)CC1

InChI Key InChIKey=HHRJZEIOBZQYGL-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50175839   

TargetCytochrome P450 2D6(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50175839(4-((1H-imidazol-4-yl)methyl)-1-(3-phenoxypropyl)pi...)
Affinity DataIC50: 30nMAssay Description:Inhibition of CYP2D6 by human liver microsome assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50175839(4-((1H-imidazol-4-yl)methyl)-1-(3-phenoxypropyl)pi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50175839(4-((1H-imidazol-4-yl)methyl)-1-(3-phenoxypropyl)pi...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50175839(4-((1H-imidazol-4-yl)methyl)-1-(3-phenoxypropyl)pi...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed