BDBM50175693 4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide::CHEMBL371967

SMILES O=C(NCCN1CCCC1)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1

InChI Key InChIKey=RHPZNJJJKFQSAG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175693   

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175693(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)-N...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against IKK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50175693(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)-N...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against IKK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50175693(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)-N...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against IKK complex isolated from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed