BDBM50175490 7-methyl-3-[2-(4-o-tolyl-piperazin-1-yl)-ethyl]-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one::CHEMBL197078

SMILES CN1CCc2c(C1)sc1ncn(CCN3CCN(CC3)c3ccccc3C)c(=O)c21

InChI Key InChIKey=DOSWXEACORUGRU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50175490   

Target5-hydroxytryptamine receptor 1A(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50175490(7-methyl-3-[2-(4-o-tolyl-piperazin-1-yl)-ethyl]-5,...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [35S]GTP-gamma-S from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50175490(7-methyl-3-[2-(4-o-tolyl-piperazin-1-yl)-ethyl]-5,...)
Affinity DataKi:  3.5nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed