BDBM50175472 3-(2-{4-[2-(2,2-dimethyl-propoxy)-phenyl]-piperazin-1-yl}-ethyl)-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one::CHEMBL371094

SMILES CN1CCc2c(C1)sc1ncn(CCN3CCN(CC3)c3ccccc3OCC(C)(C)C)c(=O)c21

InChI Key InChIKey=RWUZHFAQAJYRLS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50175472   

Target5-hydroxytryptamine receptor 1A(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50175472(3-(2-{4-[2-(2,2-dimethyl-propoxy)-phenyl]-piperazi...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [35S]GTP-gamma-S from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50175472(3-(2-{4-[2-(2,2-dimethyl-propoxy)-phenyl]-piperazi...)
Affinity DataKi:  5.40nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed