BDBM50175364 3-(((R)-2-((R)-1-hydroxy-2-(1-(4-methoxyphenyl)-2-methylpropan-2-ylamino)ethyl)pyrrolidin-1-yl)methyl)benzonitrile::CHEMBL370671

SMILES COc1ccc(CC(C)(C)NC[C@@H](O)[C@H]2CCCN2Cc2cccc(c2)C#N)cc1

InChI Key InChIKey=ISFYKUAUIAMUIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175364   

TargetExtracellular calcium-sensing receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175364(3-(((R)-2-((R)-1-hydroxy-2-(1-(4-methoxyphenyl)-2-...)
Affinity DataIC50: 2.67E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed