BDBM50175018 4,7,8-trihydroxy-2,3,3-trimethyl-9-(3-methylbut-2-enyl)-2,3-dihydrofuro[3,2-b]xanthen-5-one::CHEMBL371024::cudraxanthone M

SMILES [#6]-[#6]1-[#8]-c2cc3oc4c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c(-[#8])cc4c(=O)c3c(-[#8])c2C1([#6])[#6]

InChI Key InChIKey=CPBAXXJDYLIVPC-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50175018   

TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50175018(cudraxanthone M | 4,7,8-trihydroxy-2,3,3-trimethyl...)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50175018(cudraxanthone M | 4,7,8-trihydroxy-2,3,3-trimethyl...)
Affinity DataIC50: 5.68E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50175018(cudraxanthone M | 4,7,8-trihydroxy-2,3,3-trimethyl...)
Affinity DataIC50: 186nMAssay Description:Inhibition of Clostridium perfringens neuraminidase by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50175018(cudraxanthone M | 4,7,8-trihydroxy-2,3,3-trimethyl...)
Affinity DataKi:  98nMAssay Description:Competitive inhibition of Clostridium perfringens neuraminidase by Lineweaver-Burke plot and Dixon plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50175018(cudraxanthone M | 4,7,8-trihydroxy-2,3,3-trimethyl...)
Affinity DataKi:  510nMAssay Description:Apparent binding affinity at Clostridium perfringens neuraminidase by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed