BDBM50174967 (R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylethyl)-N-methyl-5-(methylsulfonamido)-2,3-dihydrobenzofuran-2-carboxamide::CHEMBL434933

SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)[C@H]1Cc2cc(NS(C)(=O)=O)ccc2O1

InChI Key InChIKey=YQHGOBDJEDJFJK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174967   

TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50174967((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50174967((R)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)
Affinity DataKi:  1.30nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed