BDBM50174950 6-Sulfamoyl-chroman-2-carboxylic acid [(S)-2-((S)-3-hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-methyl-amide::CHEMBL197123

SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C1CCc2cc(ccc2O1)S(N)(=O)=O

InChI Key InChIKey=FNETXDSKTUEDMJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174950   

TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50174950(6-Sulfamoyl-chroman-2-carboxylic acid [(S)-2-((S)-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50174950(6-Sulfamoyl-chroman-2-carboxylic acid [(S)-2-((S)-...)
Affinity DataKi:  3.30nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed