BDBM50174774 2‐({[3‐chloro‐4‐(4‐chloro‐2‐ hydroxyphenoxy)phenyl]amino}methyl)benzonitrile (10)::2-((3-chloro-4-(4-chloro-2-hydroxyphenoxy)phenylamino)methyl)benzonitrile::CHEMBL200492

SMILES Oc1cc(Cl)ccc1Oc1ccc(NCc2ccccc2C#N)cc1Cl

InChI Key InChIKey=VIBJLVSRNLWMPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174774   

TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM50174774(CHEMBL200492 | 2‐({[3‐chloro‐4&#...)
Affinity DataIC50: 16nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details Article
PubMed
TargetEnoyl-acyl-carrier protein reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50174774(CHEMBL200492 | 2‐({[3‐chloro‐4&#...)
Affinity DataIC50: 560nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed