BDBM501747 N-Cyclopentyl-3-(5-((5-(2-((3S,5R)-3,5-dimethylpiperazin-1-yl)ethoxy)-7-methyl-9-oxo-9H-xanthen-3-yl)oxy)pyridin-2-yl)propanamide::US11028064, Example 61

SMILES C[C@H]1CN(CCOc2cc(C)cc3c2oc2cc(Oc4ccc(CCC(=O)NC5CCCC5)nc4)ccc2c3=O)C[C@@H](C)N1

InChI Key InChIKey=YNCCIYJGALHSRG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501747   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Auckland Uniservices

US Patent
LigandPNGBDBM501747(N-Cyclopentyl-3-(5-((5-(2-((3S,5R)-3,5-dimethylpip...)
Affinity DataIC50: 100nMAssay Description:IC50 values were determined using the Z′-LYTE activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Auckland Uniservices

US Patent
LigandPNGBDBM501747(N-Cyclopentyl-3-(5-((5-(2-((3S,5R)-3,5-dimethylpip...)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 values were determined using the Z′-LYTE activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent