BDBM50174682 (2S,3R,4S,5S,6R)-2-(3-(4-methoxyphenethyl)-1H-indol-4-yloxy)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol::CHEMBL200394

SMILES COc1ccc(CCc2c[nH]c3cccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c23)cc1

InChI Key InChIKey=ZETFQCZSERGWIR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50174682   

TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50174682((2S,3R,4S,5S,6R)-2-(3-(4-methoxyphenethyl)-1H-indo...)
Affinity DataIC50: 163nMAssay Description:Inhibitory activity towards human SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50174682((2S,3R,4S,5S,6R)-2-(3-(4-methoxyphenethyl)-1H-indo...)
Affinity DataIC50: 611nMAssay Description:Inhibitory activity towards human SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50174682((2S,3R,4S,5S,6R)-2-(3-(4-methoxyphenethyl)-1H-indo...)
Affinity DataIC50: 611nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50174682((2S,3R,4S,5S,6R)-2-(3-(4-methoxyphenethyl)-1H-indo...)
Affinity DataIC50: 163nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed