BDBM50174356 CHEMBL193753::[5-Fluoro-2-methyl-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-acetic acid

SMILES Cc1c(CC(O)=O)c2cc(F)ccc2n1S(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=UNZRWCRCVPJLCE-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174356   

TargetProstaglandin D2 receptor 2(Human)
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174356([5-Fluoro-2-methyl-1-(toluene-4-sulfonyl)-1H-indol...)
Affinity DataIC50: 2.18E+3nMAssay Description:Concentration required to inhibit PGD-2 (10 nM) stimulated [Ca2+] flux in CHO cells expressing human CRTH2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174356([5-Fluoro-2-methyl-1-(toluene-4-sulfonyl)-1H-indol...)
Affinity DataKi:  457nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174356([5-Fluoro-2-methyl-1-(toluene-4-sulfonyl)-1H-indol...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards human DP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed