BDBM50174037 4-{2-[3-(4-Sulfamoyl-cyclohexa-1,5-dienyl)-thioureido]-ethyl}-benzenesulfonamide::CHEMBL365558

SMILES NS(=O)(=O)c1ccc(CCNC(=S)Nc2ccc(cc2)S(N)(=O)=O)cc1

InChI Key InChIKey=PVSWUJNBHHDSMN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50174037   

TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50174037(4-{2-[3-(4-Sulfamoyl-cyclohexa-1,5-dienyl)-thioure...)
Affinity DataKi:  3nMAssay Description:Inhibitory activity against human Carbonic anhydrase IX (hCA IX)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50174037(4-{2-[3-(4-Sulfamoyl-cyclohexa-1,5-dienyl)-thioure...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against human Carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50174037(4-{2-[3-(4-Sulfamoyl-cyclohexa-1,5-dienyl)-thioure...)
Affinity DataKi:  37nMAssay Description:Inhibitory activity against human Carbonic anhydrase I (hCA I)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50174037(4-{2-[3-(4-Sulfamoyl-cyclohexa-1,5-dienyl)-thioure...)
Affinity DataKi:  79nMAssay Description:Inhibitory activity against human Carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed