BDBM50173376 CHEMBL198114::N-Ethyl-N-{1-[3-(4-methanesulfonylamino-phenyl)-3-phenyl-propyl]-piperidin-4-yl}-2-(4-methanesulfonyl-phenyl)-acetamide

SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccc(NS(C)(=O)=O)cc2)CC1)C(=O)Cc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=ZIJRVERIGYOJGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173376   

TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50173376(N-Ethyl-N-{1-[3-(4-methanesulfonylamino-phenyl)-3-...)
Affinity DataIC50: 24nMAssay Description:Inhibition of MIP-1beta stimulated calcium transients in CCR5-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50173376(N-Ethyl-N-{1-[3-(4-methanesulfonylamino-phenyl)-3-...)
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed