BDBM50173267 1'-cyclooctylmethyl-1-(2-hydroxyethyl)spiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-2-one::CHEMBL380603

SMILES OCCN1C(=O)C2(CCN(CC3CCCCCCC3)CC2)c2ccccc12

InChI Key InChIKey=IXGOFFNUXCZZJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173267   

TargetMu-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50173267(1'-cyclooctylmethyl-1-(2-hydroxyethyl)spiro[2,3-di...)
Affinity DataIC50: 1.69E+3nMAssay Description:Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50173267(1'-cyclooctylmethyl-1-(2-hydroxyethyl)spiro[2,3-di...)
Affinity DataIC50: 290nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed